Webinar Archive

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Recent Webinars

  • New Solution for large scale Genomic studies

    Speaker: Peer Staehler, CSO

    Published: January 2010

    Abstract: The recent explosion of genome wide association studies (GWAS) and whole genome sequencing projects has fueled the need for efficient and cost effective methods of resequencing targeted regions. The febit HybSelect™ technology provides a robust method for targeted enrichment that allows researchers to select specific genomic regions of interest for variant discovery or validation experiments. The Applied Biosystems SOLiD™ 3 System provides a highly accurate, massively parallel Next Generation Sequencing platform that enables large scale resequencing to be conducted more rapidly and cost effectively than previously possible.
  • High Throughput Targeted Genomic Sequencing Using SOLiD and the HybSelect Platform

    Speaker: Jack Leonard, Ph.D.

    Published: November 2009

    Abstract: Massively parallel DNA sequencing technologies, partnered with sequence capture methodologies, have accelerated the investigation of specific genomic regions while reducing the time, cost, and effort needed to interrogate multiple loci. After automated sequence capture with HybSelect, targeted genomic sequencing was carried out on the SOLiD System. We demonstrated that high levels of multiplexing are achievable by combining HybSelect parallel sample processing capabilities with the new bar-coding reagents for SOLiD from Life Technologies. Up to 320 bar-coded samples can be sequenced every 6 days using a SOLiD Sequencing System with a febit Geniom RT Analyzer. The sample throughput will continue to increase with the introduction of additional bar-codes.
  • The Power to Detect - HybSelect for Targeted Sequence Capture

    Speaker: Jack Leonard, Ph.D.

    Published: March 2009

    Abstract: The proliferation of Next-Gen Sequencing (NGS) platforms has increased DNA sequencing throughput by orders of magnitude, however, it still takes months and several hundreds of thousands of dollars to finish a typical mammalian-sized genome at a reasonable depth of coverage. Integrated HybSelect automation allows walk-away convenience and only requires 30 minutes of hands-on time, offering the simplest targeted sequence capture method available.
  • The brave new world of non-coding RNAs

    Speaker: Prof. Alexander Huettenhofer

    Published: February 2009

    Abstract: In cells from all organisms studied to date two different types of RNAs have been found: messenger RNAs (mRNAs), which are translated into proteins, and so-called non-protein-coding RNAs (ncRNAs), which are not translated into proteins but function at the level of the RNA itself. How many of these ncRNAs really exist in the genomes of model organisms and what are their functions?
  • Beyond miRNAs - ncRNA Analysis on Geniom Biochips

    Speaker: Sonja Vorwerk, Ph.D.

    Published: December 2008

    Abstract: Approximately every 3-4 months a new release of the miRBase becomes available, so analysis tools need to be flexible to incorporate these changes. In addition, there is more than just miRNAs in the field of non-coding RNAs, which are not yet covered by high-throughput technology at the moment.
  • The Human Genome as an RNA Machine

    Speaker: John Mattick, Ph.D.

    Published: June 2008

    Abstract: The human genome contains about 20,000 protein-coding genes, surprisingly the same number as those in tiny worms. The basis for our complexity - it seems - lies in the 98% of our genome (the so-called „junk“ DNA). Professor Matticks studies indicate that these non-protein-coding RNAs (ncRNAs) form a massive hidden network of regulatory information.